Quantitative analysis of wobble splicing indicates that it is not tissue specific

Adipogenesis: It Is Not Just Lipid That Comprises Adipose Tissue

Adipogenesis is the initial component of forming cells (adipocytes) capable of assimilating lipid. Lipid metabolism is a metabolic process whereby lipid is stored for use when energy is required. Both processes involve cellular and molecular components. The gene regulations of each are different and (yet) confusingly, markers for both are used interchangeably. The focus of this paper is to prov...

Lichen amyloidosus without itching indicates that it is not secondary to chronic scratching.

Sir, The origin of lichen amyloidosus (LA) is controversial. It is a form of primary cutaneous amyloidosus in which fibrillar proteinaceous material is deposited solely in the skin, without associated systemic manifestations. LA is typically highly pruritic, and the deposition of fibrillar material has generally been considered to be secondary to the scratching induced by other subjacent prurit...

A genome-wide analysis indicates that yeast pre-mRNA splicing is predominantly posttranscriptional.

Recent ChIP experiments indicate that spliceosome assembly and splicing can occur cotranscriptionally in S. cerevisiae. However, only a few genes have been examined, and all have long second exons. To extend these studies, we analyzed intron-containing genes with different second exon lengths by using ChIP as well as whole-genome tiling arrays (ChIP-CHIP). The data indicate that U1 snRNP recrui...

Academic nepotism – all that glitters is not gold

Dear Editor With increasing emphasis on publications forfaculty recruitment, career advancementand obtaining research grants, the issues relatedto author kinship and academic nepotism havegrown significantly and these probably reflectthe inflationary growth rather than the optimalgrowth warranted due to increasing researchcomplexity. Allesina S (1) measured the fullmagnitude of nepotism in the ...

Quantitative Dengue Test: Is it Practical for Clinical Practice?